Molecular Mechanism of Citrate Efflux by the Mitochondrial Citrate Transporter CT in Filamentous Fungus Mucor circinelloides WJ11
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چکیده
منابع مشابه
Antioxidants Potential of the Filamentous Fungi (Mucor circinelloides)
Three important strains of Mucorcircinelloides grown in complete and minimal media for specified period (72 h, 120 h and 168 h) under submerged fermentation conditions were investigated for their potential antioxidants/secondary metabolite production. All mycelial extracts demonstrated effective antioxidant activities in terms of β-carotene/linoleic acid bleaching, radical scavenging, reduction...
متن کاملThe mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis
Dysregulation of the pathways that preserve mitochondrial integrity hallmarks many human diseases including diabetes, neurodegeration, aging and cancer. The mitochondrial citrate transporter gene, SLC25A1 or CIC, maps on chromosome 22q11.21, a region amplified in some tumors and deleted in developmental disorders known as velo-cardio-facial- and DiGeorge syndromes. We report here that in tumor ...
متن کاملGrowth of Bacillus subtilis on citrate and isocitrate is supported by the Mg2+-citrate transporter CitM.
Bacillus subtilis 168 was assayed for its growth on tricarboxylic acid (TCA) cycle intermediates and related compounds as the sole carbon sources. Growth of the organism was supported by citrate, D-isocitrate, succinate, fumarate and L-malate, whereas no growth was observed in the presence of cis-aconitate,2-oxoglutarate, D-malate, oxaloacetate and tricarballylate. Growth of the organism on the...
متن کاملGrowth of Bacillus subtilis on citrate and isocitrate is supported by the Mg-citrate transporter CitM
Bacillus subtilis 168 was assayed for growth on TCA cycle intermediates and related compounds as sole carbon source. Growth was supported by citrate, D-isocitrate, succinate, fumarate and L-malate, whereas no growth was observed in the presence of cis-aconitate, αketoglutarate, D-malate, oxaloacetate and tricarballylate. Growth on the tricarboxylates citrate and D-isocitrate required the presen...
متن کاملUptake of α-ketoglutarate by the citrate transporter CitP drives
4 Agata M. Pudlik and Juke S. Lolkema 5 6 1 Top Institute Food and Nutrition, Wageningen, The Netherlands. 2 Molecular Microbiology, 7 Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 8 Groningen, The Netherlands. 3 The Kluyver Centre for Genomics of Industrial Fermentations 9 / NCSB, Delft, The Netherlands. 10 11 * correspondence 12 J.S. Lolkema, Center for...
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ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2021
ISSN: 1664-302X
DOI: 10.3389/fmicb.2021.673881